ALPHA LIPOIC ACID--Alpha lipoic acid is a completely natural molecule that exists deep inside every cell of our bodies...an essential component of the energy-producing part of a cell. It quickly enters the cell and protects it against free radicals. Alpha lipoic acid is both water and fat-soluble, and so can fight free radicals in any part of a cell and even in the space between cells and even protects the DNA.
The antioxidant alpha lipoic acid helps to block such damage and it may improve the glucose lowering action of insulin. By improving the regulation of blood sugar glycation is reduced and our protein structures maintained. Alpha lipoic acid increases blood flow to the nerves and improves the transmission of nerve impulses. Many of the difficult symptoms of kundalini can be improved by the use of Alpha lipoic acid, especially during the acute phase to avoid nerve damage, fatigue, inflammation, numbness, tingling by supporting nerve growth and liver function. This powerful antioxidant will help with heart strength, liver toxicity, boost the immune system preserve brain cells, and help in energy production. Alpha Lipoic Acid improves nerve blood flow, reduces oxidative stress, and improves nerve conduction. It significantly lowers blood sugar levels while increasing glycogen storage in muscles and liver.
Alpha lipoic acid also regenerates the levels of vitamin C and E, glutathione and coenzyme Q10. Alpha lipoic is vital for converting glutathione back and forth from its oxidized to its reduced form. Besides its antioxidant function alpha lipoic acid is the first coenzyme necessary in the conversion of glucose to ATP, and helps cells take up sugar and use it for fuel much more efficiently. Since alpha lipoic acid is found naturally in the mitochondria it can determine the rate of metabolism. A higher energy level allows the cell to take in more nutrients, remove wastes, and replace damaged components. Thereby Alpha lipoic counters aging by increasing energy production, allowing the cell to uptake, detoxify and heal more efficiently.
The Acetyl L-carnitine combined with Alpha Lipoic Acid protects both the membranes and DNA of the mitochondria, and this is extra important during kundalini. Considering the breakdown and reconstitution of cells during metamorphosis one can assume that heavy metals, such as mercury, lead and cadmium, are freed to roam and create untold oxidative damage; taking alpha-lipoic acid and cysteine (NAC) will help chelate these metals so they can be removed from the body.
Alpha Lipoic acid in loose powder form is unpalatable, however it is toned down by mixing it into your herb mix and chugging it in a shot of apple juice. Otherwise encapsulate it yourself or by it already encapsulated.
BIOFLAVONOIDS--Bioflavonoids might be one of the very best anti-oxidants to reduce inflammation and free radical damage. Inflammation occurs when immune cells such as neutorphils overproduce free radicals, causing damage to healthy cells in the vicinity. Since the immune system during awakening is activated in a non-ordinary fashion we need to modulate its aggression and promote balance. To temper the fire so to speak. Bioflavonoids inhibit free radical creation by reducing the production of leukotrienes--the chemical messengers that summon white blood cells. They also inhibit histamine production and are potent antimicrobial and antiviral agents. Wolfberries, blueberries, bilberries, cranberries, bluegreen algae and other colorful plant material such as spinach should be ingested during awakening for this purpose. These bioflavonoid foods enhance cognitive behavior, and improves signal transmission of neurotransmitters and hormones, psychomotor performance, and acetylcholine on smooth muscles and glands (i.e.: muscarinic receptor sensitivity.)
CALCIUM-2 AEP--Ca-2-AEP is an essential factor for cell membrane integrity and sensitivity, protecting the cell from penetration by toxins and pathogens. It binds fatty acids and electrolytes to the cell membrane structure that generates the cells electrical charge. Ca-2-AEP is essential for neurotransmission, nerve impulse generation, and muscular contractions and increases the activity of various neurotransmitters, improves cellular membrane signaling and receptor sensitivity.
L-CARNITINE--Carnitine appears to build up acetylcholine and possibly dopamine and may reduce deposits of lipfuscin (AGE's), that is accumulations of crosslinked molecules in the cells. It may be more effective that Piracetam in cognitive-enhancing and rebuilding the brain. It's a natural antidepressant and increases energy and endurance. It acts to increase energy by carrying fat across the cell membrane and into the mitochondria. Energy is then stored as ATP. It reduces the metabolites of fats (ketones) in the blood from incomplete fat metabolism and reduces hyperammonemia. Carnitine is most concentrated in the heart, sperm, and brain, especially the cerebellum. L-Carnitine may be equal to or better as a cognitive enhancer than ALC. Acetyl-L-Carnitine (ALC) has mitochondrial membrane normalizing effects, while L-Carnitine is usually used for its cardiovascular, performance-enhancing, and lipid-normalizing benefits. ALC resensitizes cholinergic, serotonergic, and GABA-ergic neurotransmitter systems, reduces age-related loss of cortisol receptors normalizing the adaptive homeostat. Chronic stress impairs the reproductive homeostat (hypothalamo-pituitary-ovarian axis). ALC normalized blood testosterone levels, as well as hypothalamic beta endorphin (BEP) and gonadotropin releasing hormone (GnRH) concentrations from the hypothalamus, thereby restoring luteinizing hormone (LH).
L-CARNOSINE--The antioxidant amino acid L-Carnosine is
believed to inhibit the formation of crosslinks between proteins which
have been glycated and may even reverse glycation. The Life Extension
Foundation calls carnosine the most important antiaging compound. Use
in conjunction with alpha lipoic acid for maximum free radical
protection during awakening. Taking Carnosine as its precursors alanine
and histidine is much cheaper. During stress histidine is needed more
than any other amino acid.
CHOLINE—Keeping up a rich supply of the B Vitamin Choline is
especially important during kundalini to maintain the inhibiting side
of the nervous system and the myelin surrounding the nerves. Choline in
combination with another B vitamin Inositol form Lecithin which mostly
composes the myeline sheath—the protective coating for nerves. Choline
is found as phosphatidylcholine (or lecithin) in the phospholipids
bilayer of cell membranes. The brain is rich in lecithin, especially so
in geniuses. Choline is a building block for Acetylcholine which is the
parasympathetic nervous systems primary neurotransmitter, and remember
that excessive on-switch activity will tend to burn out the off-switch
chemicals as well. Acetylcholine is a neuromuscular messenger which
enables nerves to communicate with muscle cells therefore facilitating
muscle control and tone as well as memory, long-term planning, mental
focus, mood elevation, sexual activity and other functions. Pantothenic
acid, B5 is needed for acetylcholine production.
Lecithin plays an essential role in the body's fat chemistry; it dissolves cholesterol and keeps the arteries from clogging. Lecithin is the main component of liver cells and helps to eliminate fats from the liver. Lecithin is known to purge the cells of LDL. It is useful for drug detoxification, cell membrane fluidity, viral infections and smoking withdrawal. It is best taken in its natural form from corn, soybeans, egg yolks, yeast, wheat germ and whole grains and seeds because according to Pritikin the refined product can actually cause the same problems as other fats. Manganese conserves acetylcholine. The adaptogenic herb Ashwagandha root inhibits acetylcholinesterase, an enzyme which breaks down acetylcholine and even promotes the formation of dendrites. Choline is a precursor to Betaine, an osmolyte used yb the kidney to control water balance. Symptoms for deficiency of the B vitamin Choline include kidney failure, high cholesterol and high blood pressure.
The omega-3 fatty acid Docosahexaenoic acid (DHA) found in fish oil
also increases choline and acetylcholine levels in the brain. The
lecithin extract phosphatidyserine supports acetylcholine and improves
motivation, initative and socialization. Brain cell survival is highly
dependent on the availability of DHA to facilitate the incorporation of
phosphatidyserine into its membranes.
Another lecithin extract L-Alpha Glycerylphosphorylcholine (Alpha-GPC) sometimes called GPC (glycerophosphocholine) is a naturally occurring phospholipid precursor and metabolite. It increases in endogenous human Growth Hormone (hGH) secretion by the anterior pituitary in conjunction with Growth Hormone Releasing Hormone (GHRH. Alpha-GPC contributes directly to improved mental focus and cognitive function through stimulation of the enzymatic synthesis of phosphatidylcholine (PC) in nerves, muscle cells and all cell membranes, counteracting the age-related decrease in phospholipid (PC) biosynthesis.
GPC acts as a precursor of acetylcholine (ACh) thus activates cholinergic transmission which permits the development of more strength from work-outs and training programs, plus reducing levels of somatostatin in the hypothalamic-pituitary axis. Elevations in blood and tissue levels of the essential nutrient, choline, which supports improved lipotrophic functions in the liver. The fatty liver condition normally associated with degenerative disease can be prevented and possibly even eliminated with increased levels of choline. Alpha-GPC also acts synergistically with endogenous or supplemental S-adenosyl-L-methionine (SAMe) and folic acid, vitamin B12 and vitamin B6 to facilitate methyl group transfers in the brain and liver. GPC improves balance and coordination as a result of normalized nerve transmission in the brain, and in cardiac, skeletal and smooth muscles.
Di-Methyl-Amino-Ethanol (DMAE) is a naturally occurring compound
that is present in significant amounts in fish. DMAE promotes the
formation of acetylcholine, an important brain neurotransmitter,
increasing memory, learning and intelligence. Acetylcholine and its
precusor choline are unable to cross the blood-brain barrier very well.
The body makes acetylcholine from choline as it is needed. DMAE is
basically a choline molecule with one methyl group missing from the
nitrogen. DMAE is more able to cross the blood-brain barrier than
choline. Once inside the brain, an enzyme performs a methylation that
converts DMAE into choline. So, taking DMAE increases the brain's
potential to make neurotransmitters.
CREATINE--Creatine is an amino acid made from glycine and arginine in the kidneys. It increases blood sugar and Growth Hormone. Creatine in the form of phosphocreatine (creatine phosphate) is an important store of energy in muscle cells. During intense exercise lasting around half a minute, phosphocreatine is broken down to creatine and phosphate, and the energy released is used to regenerate the primary source of energy, adenosine triphosphate (ATP). Output power drops as phosphocreatine becomes depleted, because ATP cannot be regenerated fast enough to meet the demand of the exercise. It follows that a bigger store of phosphocreatine in muscle should reduce fatigue during sprinting. Extra creatine in the muscle may also increase the rate of regeneration of phosphocreatine following sprints, which should mean less fatigue with repeated bursts of activity in training or in many sport competitions.
L-DEPRENYL--or Selegiline, is a MAO-B inhibitor. Taking 2 x 5mg/day irreversibly inhibits over 90% of MAO-B in the basal ganglia, the location of over 80% of dopamine leading to a 40%-70% increase in synaptic dopamine. L-Deprenyl has immune-system-boosting and protects neurons from hypoxic or oxidative damage. L-Deprenyl induced rapid increases in NO production in brain tissue and cerebral vessels leading to vasodilation. Its use increases the level of tyrosine hydroxylase, growth hormone, cerebral nitric oxide and the production of key interleukins. L-Deprenyl offers protection against DNA damage and oxidative stress by free radicals and against excitotoxic damage from glutamate. In addition, L-Deprenyl stimulates the release of the body's own antioxidant superoxide dismutase (SOD). L-Deprenyl protects permeability of the mitochondria membrane through directly interacting with its pore-forming structures. L-Deprenyl tends to extend the lives of rats by 20%; enhances drive, libido, endurance and improves cognitive performance.We tend to lose around 13% of our dopamine cells a decade in adult life. L-Deprenyl protects the brain's dopamine cells from oxidative stress and retards the breakdown not just of dopamine but of phenylethylamine as well.
DHEA--Steroid hormones and stress hormones. If you are making up the antioxidant formula 2 from powders bought at beyond-a-century you only need about 1 teaspoon DHEA mixed into your entire batch. 1.5 teaspoons if you are a man or are very devitalized. Hormones should not be taken during the priming years or the main peaking months because the body is already maximizing its hormonal output at these times. Only take DHEA if you are over 40 years and are on the downside of the awakening and the hormonal herbs are not quite doing it for you.
DMAE--Dimethylaminoethanol is an antioxidant membrane stabilizer found in fish. It is a precursor to choline and acetylcholine. Unlike choline, it easily passes the blood/brain barrier where it stimulates the cholinergic nervous system. DMAE actually intersperses and becomes part of the cell plasma membrane, making the membrane is more able to resist stress and therefore is stabilized. DMAE also gives some protection from free radicals and because it prevents the breakdown of the cell plasma membrane it prevents the production of arachidonic acid and its consequent inflammation. DMAE also increases cognitive function.
As we age the chemicals and nutritional precursors that give tone to muscles and skin, start to diminish as a result of years of free-radical damage. Once aging begins, the amount of acetylcholine produced, as well as the effect of the chemical on the muscle, is diminished. Increasing the levels of acetylcholine produces a stronger muscle contraction and firmer skin.
ESSENTIAL FATTY ACIDS--Getting plenty of the essential fatty acids Omega 3 and Omega 6 is essential during metamorphosis to help protect the nerve sheaths and cell membranes from free radical damage.
Omega 3 or EPA, (alpha linolenic acid)--is found in fish oils. The fish with the highest content of EPA are anchovy, salmon, herring then mackerel. Research has shown that EPA has reduced triglycerides by 64% and cholesterol by 24% after only one month on a diet high in fish oil. Omega 3 stimulates endothelial-derived nitric oxide and enhances the production of prostacyclin, a prostaglandin that produces vasodilation and less sticky platelets.
Omega 6 or GLA, (gamma linolenic acid)--is found in Borage and Evening Primrose oil. Cis-linolenic acid is converted to GLA in the body and is found in safflower, sunflower and corn oils in the greatest quantity.
Essential fatty acids (EFA) are necessary for all metabolic functions and must be included in the diet as the body cannot manufacture them. In the body essential fatty acids are converted into prostaglandins. Prostaglandins are cell regulators that modify pituitary responses to hypothalamic hormones, including thyroid-stimulating hormone (TSH) and adrenocorticotropic hormone (ACTH). Prostaglandins are short lived hormone-like substances that act in the regulation of all cellular metabolic processes in the reproductive, cardiovascular, immune, digestive and central nervous systems. They also act in the body's thermoregulation, calorie loss and restoring insulin sensitivity.
EFA's stimulate the release of Growth Hormone and alters the response of the thyroid gland to thyroid hormones. GLA and EPA reduce appetite, reduce blood platelet stickiness, relax blood vessels, lower blood pressure, lower triglyceride levels, relieve diabetes, improve immunity, protect from cancer, suppress inflammation, reduces eczema and allergy symptoms, help arthritis, skin hair and nail conditions.
One of the main functions of essential fatty acids are that they are the main component of cell membranes, governing membrane fluidity and cell receptor sensitivity. Researchers have found that exchanges of materials between the inside and the outside of the cell are more effective if there are sufficient EFA's in the cell membranes by promoting membrane fluidity. Gastrointestinal complaints including irritable bowel syndrome can be improved with adequate EFA's because certain prostaglandins govern the secretion of the protective stomach coating that prevents digestive acids from damaging stomach walls.
Getting your Omega oils from plant sources is best these days with the fish situation being the way it is...hemp is particularly good. Because EFAs make up a large portion of the brain, hemp is especially beneficial for brain health and memory. Hemp also contains phytosterols, which have been shown to reduce total blood cholesterol by an average of 10 per cent and low-density lipoprotein (LDL) cholesterol by an average of 13 per cent. Find a good source of fresh hemp seeds with the hulls still intact and grind with up with water to make a milk, then sieve. Or get them hulled to put on salads or in stirfries etc…A mixture of flaxseed and hemp seed will supply Omegas 3 &6.
Ideally, one third of the fat consumed should be Essential Fatty Acids (EFAs): Omega-6 Linoleic acid (LA) and Omega-3 linolenic acid (LNA). These EFAs are precursors to the prostaglandins, short-lived hormone-like substances that regulate many functions in all tissue. At least 10% of daily calories should be Omega-6 and at least 2% Omega-3. A higher ratio of Omega-6 to Omega-3 is more advantageous in stemming fatty degeneration diseases. Flax seed oil is 58% Omega-3, but it contains only 14% Omega-6. Hemp seed oil is 55% Omega-6 and 25% Omega-3, making it the best seed oil for optimal health and prevention of fatty degeneration.
A diet overly high in Omega 6 and poor in Omega 3 increases insulin resistance and Type 2 diabetes, Hyperglycemia is a source of free radicals when the glucose rise above 120 mg% in the blood. Free radicals created by chronic hyperglycemia assault beta cells of pancreas worsening glycemic control.
The omega-3 fatty acid Docosahexaenoic acid (DHA), constitutes 30-50% of the total fatty acid content of the brain, especially prominent in the cell membranes. Most fish oil supplements contain 12% DHA—cod liver oil contains large amounts of DHA and EPA. Most of the DHA in fish and other more complex organisms originates in microalgae of the genus Schizochytrium, and concentrates in organisms as it moves up the food chain. Most animals make very little DHA metabolically. The inclusion of plentiful DHA in the diet improves learning ability, whereas deficiencies of DHA are associated with deficits in learning. DHA is a major fatty acid in sperm and brain phospholipids, especially in the retina. DHA is taken up by the brain in preference to other fatty acids and the turnover of DHA in the brain is very fast.
Dietary DHA can reduce the level of blood triglycerides in humans, which may reduce the risk of heart disease. Studies show a reduced blood level of omega-3 fatty acids in people with depression. It controls inflammation and decreases free radical induced levels of lipid peroxide in the hippocampus (learning and memory). DHA also increases choline and acetylcholine levels in the brain. The lecithin extract phosphatidyserine supports acetylcholine and improves motivation, initative and socialization. Brain cell survival is highly dependent on the availability of DHA to facilitate the incorporation of phosphatidyserine into its membranes.
GLUTATHIONE--Glutathione (GSH) is a sulfhydryl antioxidant, antitoxin, enzyme cofactor and is the major repair enzyme. Glutathione is one of the most highly concentrated intracellular antioxidants found in animals, plants, and microorganisms. Glutathione being water soluble is found mainly in the cell cytosol and other aqueous phases of the living system. It plays an important role in cell detoxification, DNA and protein synthesis, transport processes and in the removal of oxidants. Mitochondria from most mammalian cells do not contain catalase (the heart being an exception), implying that glutathione (GSH) in mitochondria is a major defense against the potential toxic effects of endogenously produced ROS in the electron transport system.
GSH depletion may be the ultimate factor determining vulnerability to free radical attack, cell death by oxidation and has been documented in many degenerative conditions. Glutathione improves macrophage activity. It protects from and repairs damage caused by free radicals and UV. It is good for cancer, allergies, cataracts, arthritis and smokers.
GSH has a potent electron-donating capacity and this is reducing power is most expressed by GSH where its concentrations are highest, as in the liver. Glutathione has the ability to make a toxic compound water-soluble so it can be flushed out of the body via the kidneys. Also can inhibit the oxygenation of arachridonic acid to inflammatory prostaglandins and leukotrienes.
The reducing power of GSH is a measure of its free radical scavenging, electron-donating, and sulfhydryl-donating capacity. Reducing power is also the key to the multiple actions of GSH at the molecular, cellular, and tissue levels, and to its effectiveness as a systemic antitoxin. The two water-phase antioxidants are tightly linked: GSH can conserve Vitamin C, and conversely Vitamin C can conserve GSH.
Its full name is g-glutamylcysteinylglycine, meaning it is a combination of Cysteine, Glutamic acid and Glycine. It may be best taken in its component parts as it is cheaper than buying Glutathione and is easier to assimilate. Of all the oral GSH precursors probably the best is NAC (N-acetylcysteine). Glutathione is found in citrus, strawberries, peaches, potatoes, squash, broccoli and tomatoes. To reduce free radical damage thereby enhancing the immune system and preventing allergic reactions and auto-immune diseases like arthritis take:Aminos: Glycine, N-acetyl-Cysteine, Glutamine, Tryptophan with Cofactors: Vitamin B complex, C, E and Selenium and this will increase your glutathione levels.
N-ACETYL-CYSTEINE--Of the three amino acids needed to make glutathione--cysteine, glycine and glutamic acid--cysteine is the most crucial due to its sulphur molecule. Levels of cysteine will determine how fast we produce glutathione and how much we make. N-acetyl-cysteine or NAC is a potent antioxidant and immune stimulant, shown to enhance lung function. It enhances glutathione production more than taking glutathione itself. Protects the mitochondrial DNA from damage, and tissue free radical damage from exercise, pollution and UV radiation. Helps remove mercury and other heavy metal deposits. Barely and yogurt are particularly high cysteine foods. I wonder if barely grass juice contains lots of cysteine also.
GLUTAMINE--As well as cysteine it is recommended to take the other two aminos that make up glutathione as supplemental glycine and glutamine. Both glutamate and glutamine are forms of glutamic acid, the body easily converts the glutamine to glutamic acid. Glutamic acid readily passes the blood brain barrier and is considered a "brain fuel.
In the brain, glutamine is a substrate for the production of both excitatory and inhibitory neurotransmitters (glutamate and GABA). Glutamine is also an important source of energy for the nervous system. Glutamic acid and cysteine are necessary for glucose regulation, and can decrease cravings for alcohol and sugar. If the brain is not receiving enough glucose, it compensates by increasing glutamine metabolism for energy. Glutamine users often report more energy, less fatigue and better mood. Taking glutamine during kundalini does not appear to enflame kundalini fire, however any carbohydrate or sugar appears to do so. Hence gluatmine might be a "safe" brain fuel during kundalini while on a ketogenic or low sugar diet.
Glutamine is the most abundant single amino acid in the blood and in the muscle tissue comprising up to 60% of the amino acid pool in skeletal muscle; and is manufactured and released primarily by the skeletal muscle. Because it is important in the rapid growth of cells more is needed during stress or illness. Glutamine is utilized as a source of energy and for nucleotide synthesis by all rapidly dividing cells, such as the cells of the intestinal lining and certain immune cells thus without sufficient glutamine, the intestines atrophy and the immune function breaks down. Glutamine therapy was found to improve intestinal permeability in AIDS patients.
Glutamine serves as a nitrogen donor and a carbon donor, and is thus an important muscle-building amino acid. Glutamine's unique structure, containing two nitrogen side chains makes it responsible for 35% of the nitrogen that gets into the muscle cell. It is anticatabolic, meaning it regulates protein synthesis in muscles, sparing muscle tissue and helps replenish muscle glycogen after exercise. It is also involved in glycogen synthesis in the liver and is a building block of many other amino acids. Glutamine can increase growth hormone levels by 43% thereby slowing aging. It also improves lymphocyte proliferation. Further more it reduces insulin resistance and high blood sugar which also counteracts aging.
The amino acid glutamine strengthens the cell lining of both the small and large intestines, provides metabolic fuel for gut cells, brain cells, immune macrophages and lymphocytes. Glutamine has been reported to be helpful in reducing "leaky gut" and "brain fog". Glutamine is important as an energy source for our bodies, and is the primary fuel for the upper intestinal tract. It aids the immune system by increasing the integrity of the intestinal lining preventing toxins and pathogens from entering the bloodstream. Glutamine is also a component of folic acid. There is an association between folic acid deficiency and seizure. Disruptions of the intestinal lining may cause folate deficiency, and consequently lead to seizures.
The small intestine uses 40% of the glutamine in the body, it being the primary amino acid for the cells that line the small intestine; it nourishes and repairs them. Insufficient glutamine increases the permeability of the gut leading to leaky gut syndrome. This lets in toxins, pathogens and partially digested molecules into the blood increasing the load on the liver. The large molecules entering the bloodstream stimulate antibody production, and then the liver subsequently has to cope with the waste products of antibodies. Which again increases the demands made on glutathione and other antioxidants.
During kundalini the body's demand for glutathione goes up to cope with the free radicals and detoxification process, which robs more glutamine from the small intestine making the leaky gut syndrome worse. The extra demand for antioxidants during a kundalini awakening and the subsequent utilization of glutamine from the small intestine could be one of the main reasons for digestive upset during metamorphosis. This situation is remedied by taking glutamine and its cofactors. Glutamine protects the brain and body from ammonia toxicity. Excess ammonia interferes with the oxidative metabolism of neurons and reduces the production of ATP, the "energy molecule." In addition, ammonia gives rise to very harmful nitrogen-based free radicals.
GABA--GABA is made from the amino acid Glutamic acid (Glutamine or Glucose). It reduces anxiety, elevates the pain threshold reduces the blood pressure and heart rate and reduces compulsive behavior. GABA promotes fat loss and stimulates the production of Human Growth Hormone (HGH). GABA can be taken as a supplement (L-Glutamine), produces a calming effect on people who struggle with temporal lobe symptoms like temper, irritability, and anxiety.
GLYCINE--Glycine and glucose are the two most common amino acids in the body. Glycine is the simplest amino acid and is the only protein forming amino acid without a center of chirality, that is it is nonpolar. Because glycine has such a small side chain it can fit into many places where no other amino acid can. Hence it is the internal amino acid of a collagen helix, thus collagen is about one-third glycine. Most proteins however only contain a small quantity of glycine.
Like GABA, Glycine activates Cl- ion conductance resulting in a hyperpolarization of the neuronal membrane and an antagonism of other depolarizing stimuli. This membrane hyperpolarization makes glycine the major inhibitory neurotransmitter in the brainstem and spinal cord, where it participates in a variety of motor and sensory functions. However in the forebrain it functions in an excitatory way by promoting the actions of the major excitatory neurotransmitter glutamate at the NMDA receptors. Other amino acids, including alanine and taurine, also activate glycine receptors, but with lower potency.
Glycine may increase acetylcholine neurotransmission in the hippocampus, the memory center of the brain. This factor could be involved in having "ones life pass before ones eyes" during near death experiences. Increases blood sugar and Growth Hormone. Vitamin B6, magnesium and dimethylglycine are antiseizure and have increased speech in autistic children. Found in many foods, glycine is also synthesized in the human body where, among other functions it helps improve glycogen storage. It is utilized in the synthesis of hemoglobin, collagen and glutathione, and facilitates the amelioration of high blood fat and uric acid levels.
HISTIDINE-- The amino acid Histidine is a precursor for histamine and carnosine. It is needed for growth and for the repair of tissue, as well as the maintenance of the myelin sheaths. It is also required for the manufacture of both red and white blood cells, and is also aids in the production of gastric juices. It helps remove heavy metals from the body and to protect the body from damage caused by radiation. Schizophrenics have been found to have high levels of histidine, so they nor those suffering from bipolar (manic) depression should take histidine. Dairy, meat, poultry and fish are good sources of histidine as well as rice, wheat and rye.
HYPERZINE--Prevents the degradation of endogenus acetylcholine, promotes dendrite growth and seems to protect neurons from cell death caused by toxins. Use in conjunction with DMAE, choline and Vitamin B 5 for synergy.
MAGNESIUM--Magnesium supplementation during kundalini
awakenings is imperative due to the long periods of HPA-axis
hyperactivation and increased lipolysis. Magnesium is the fourth most
abundant mineral in the body and is essential to good health.
Approximately 50% of total body magnesium is found in bone. The other
half is found predominantly inside cells of body tissues and organs,
while only 1% of magnesium is found in blood. The mineral magnesium
(Mg) is used in building bones, manufacturing proteins, releasing
energy from muscle storage, and regulating body temperature. Calcium
(Ca) causes muscles to contract, while magnesium helps them relax.
Stress, both physical and emotional, evokes the release of the stress hormones: catecholamines and corticosteroids. These stress hormones can induce magnesium loss, and high ratios of Ca/Mg stimulate of their secretion, constituting a self-reinforcing loop. The result being that Mg deficiency and catecholamines each cause tissue Ca overload.
Adrenergic stimulation of lipolysis can intensify Mg deficiency by complexing Mg with the liberated fatty acids (FA). Short and long-term fasting has caused Mg loss for this reason. Kundalini also, because of the increased stress hormones, lipolysis and autolysis of tissues will increase the demand for Magnesium.
A low Mg/Ca ratio increases stress hormone (catecholamine) secretion, which in turn lowers tissue Mg levels. It also favors excess release or formation of factors (derived both from Fatty Acid metabolism and the endothelium: prostaglandins and fibronectin), that are vasoconstrictive and platelet aggregating. High Ca/Mg ratios lead to increased blood coagulation, which is also favored by excess fat and its mobilization during adrenergic lipolysis. Epinephrine, but not norepinephrine, significantly reduced plasma Mg in healthy men; and elevated blood catecholamines interfere with absorption of Mg in the intestinal tract.
Mg modulates smooth muscle contraction through its Ca-blockage or competition. High altitude intensive training resulted in a negative Mg balance sufficient to cause convulsions. Since the energy generation of the body goes up in kundalini there is an increase in ATP synthesis and ATP synthesis is Mg-dependent, as is phosphorylation; while cAMP levels are low in Mg deficiency. www.mgwater.com/conseq.shtml
Mg deficiencies can be caused by diuretics, stress, and dietary imbalances such as high fat, sugar, alcohol or calcium. A magnesium-rich diet consists of nuts, whole grains such as brown rice, millet, buckwheat (kasha), quinoa, whole wheat, and rye, and legumes including lentils, and beans. Chocolate is IN as far as Magnesium is concerned, cocoa powder has the most Magnesium of any food. Though try mixing the cocoa powder with dried fruit and nuts to make your own chocolaté concoctions, with the addition of some spirulina. Magnesium is lost in cooking some foods even under the best conditions. Green vegetables such as spinach are good sources of magnesium because the center of the chlorophyll molecule (which gives green vegetables their color) contains magnesium. Also high in magnesium are peanuts, pumpkin seeds, almonds, brazil nuts, dried figs, dried apricots, yeast, parsley, spinach and tofu. Recommended daily allowance is 400mg/day—with kundalini it might be somewhat higher.
PHENYLALANINE--Phenylalanine is an essential amino acid, which is a precursor to tyrosine, another amino acid. Tyrosine is then used to produce dopamine and norepinephrine, both neurotransmitters. Phenylalanine prevents the breakdown of the brains morphine like pain killers enkephalins which inflate mood and depress appetite. Increases alertness and assertiveness, suppresses appetite, and is an effective antidepressant. Helpful as a daytime GH releaser.The neurotransmitter Dopamine is made from the amino acids Phenylalanine and Tyrosine. It increases feelings of well being, alertness, sexual excitement and aggression; and reduces compulsive behavior.
Tyrosine is a natural amphetamine and precursor to adrenaline. Tyrosine might create headaches so DL-Phenylalanine is better. L-tyrosine is the first breakdown product of and similar in many effects to L-phenylalanine, but less likely to affect blood pressure. A precursor of dopamine, norepinephrine, and thyroid hormone, it may help some types of depression. The adrenal hormone Norepinephrine is made from Dopamine; it also increases well being and reduces compulsivity
Phenylalanine can be found in the following foods: soybean protein, frozen tofu, dried and salted cod, shellfish, lean meat, organ meat, skin-free chicken, cheese, milk, eggs, many seeds (watermelon, fenugreek, roasted soybean nuts), and chocolate.
PHOSPHATIDYLSERINE--PS is a phospholipid that occurs naturally in all cells of the body, with particularly high concentrations in the brain. PS has cognitive-enhancing properties probably due to its ability to sensitize acetylcholine receptors. It is an essential cell membrane component for nerve cells; playing a key role in communication across synapses between nerve cells, and reverses loss of membrane fluidity associated with age-related mental decline. PS also ameliorates elevations of stress hormones (ACTH and cortisol) and helps prevent memory loss and other cognitive decline. PS is a cortisol receptor sensitizer, resulting in improved levels and efficient use of cortisol, It is also a very effective antidepressant due to its ability to normalize the adaptive homeostat (HPA-axis). The normalizing of prolactin receptors may contribute to the many positive benefits of phosphatidylserine.
PIRACETUM--Wakes up your brain, boosts intelligence and stimulates the central nervous system. It promotes the flow of information between the left and right hemispheres of the brain, leading to increased creativity. Best taken with hydergine and choline. It appears to have a regenerative effect one nerves, and might increase the cholinergic receptors in the brain. Enhances cognition under hypoxia and has been used as an anticonvulsant in epilepsy. ANIRACETAM is a more potent, longer-lasting, fat soluble analogue of Piracetam. It has proven to be one of the best nootropics currently available.
SAMe--S-adenosylmethionine is found in all cells and is formed in the body by combining the essential amino acid methionine with ATP. SAMe is involved in the synthesis and protection of DNA, RNA, and protein, maintains mitochondrial function, restores membrane fluidity and facilitates the binding of hormones to cell receptors. SAMe forms glutathione which protects and regenerates liver and cartilage, protects neurons from hypoxia, is involved in remyelination of neurons and protects cardiovascular system from homocysteine and free radicals. Aging reduces SAMe levels. Due to the reduced sensitivity of prolactin receptors, prolactin levels are known to rise with age, consequently lowering levels of growth hormone, testosterone causing impotence. Long-term supplementation with SAMe repairs cell membrane fluidity and enhances the sensitivity of prolactin receptors, as well as GABA and beta-receptors and probably serotonin and dopamine receptors as well. When there is inadequate estrogen negative feedback via the pituitary gland, elevated prolactin can in turn contribute to elevated estrogen levels (estrogen dominance).
TAURINE--The amino acid Taurine comprises of more than 50% of the free amino acids in the heart. Taurine differs from other amino acids in that it doesn't become incorporated into proteins. It exists as a free amino acid and is one of the most abundant amino acids in muscle, blood platelets, and the developing nervous system. Taurine promotes the pumping action of the heart. Evidently taurine serves as a neurotransmitter, a regulator of salt and water balance and a stabilizer of cell membranes, a detoxifier, and regulates cell membrane excitability. Taurine is involved in calcium metabolism in the heart and may affect the entry of calcium into the heart muscle cells where it is essential to the generation and transmission of nerve impulses. It can also prevent heart beat irregularities caused by adrenalin. Taurine in combination with other cardio-protective nutrients may be good to take during the heart expansion period of the peak: coenzyme Q10, L-Carnitine and Magnesium.
It protects and stabilizes the brains fragile tissues and is the second most plentiful amino acid in the brain after glutamic acid. Taurine facilitates Na, P, Ca and Mg in and out of cells, and electrically stabilizes cell membranes. Taurine is a component of bile and fat digestion, it plays a role in cellular defense against light damage to the eye and may prevent epileptic seizures in some cases. Under the stressful and hyper-activation conditions of kundalini taurine supplementation will help with the seizure-like hypertension and heart inflation. Taurine supplementation during kundalini maybe an advisable precaution especially for vegetarians. Cysteine (NAC) and B6 increases taurine levels, whereas taking taurine directly may irritate the gut. Zinc enhances taurine's effect. Since stress can deplete the body of zinc and B6 it may also lower taurine levels.
Through its role in calcium metabolism in the brain, it plays a major part in the release of neurotransmitters. Taurine may inhibit the release of excitatory neurotransmitter such as norepinephrine and acetylycholine and suppress adrenaline release. Thus is a safe tranquilizer. As inhibitory neurotransmitters taurine appears metabolically and structurally similar to GABA and glycine.
TRYPTOPHAN (5-HTP)--The neurotransmitter serotonin is made from the amino acid Tryptophan. Serotonin neural circuits help counterbalance the tendency of brain dopamine and noradrenaline circuits to encourage over-arousal. It calms, elevates pain threshold, promotes relaxation, sleep and feeling of well being, reduces aggression and compulsive behavior and increases confidence and concentration.
Taking tryptophan while under elevated cortisol-stress conditions might supply little extra serotonin to the brain, because of cortisol's activation of an enzyme in the liver that breaks down tryptophan (tryptophan pyrrolase). Vitamin B3 inhibits liver tryptophan pyrrolase and B3 also activates the enzyme that converts tryptophan to 5HTP. Thus taking 100mg B3 several times daily with meals will also serve to enhance the effectiveness of low-moderate tryptophan doses. Taking 50mg vitamin B6 once or twice daily with meals will also augment tryptophan-serotonin conversion, since B6 activates the decarboxylase enzyme that converts 5HTP to serotonin. Melatonin actually promotes increased brain serotonin through its ability to reduce cortisol levels, and reduced cortisol levels will lessen the activity of liver pyrrolase, the enzyme that degrades tryptophan. Magnesium also helps lower cortisol. And St John's Wort is a mild MAO inhibitor which reduces the reuptake of serotonin in the brain increasing synaptic levels and it is also a cortisol inhibitor. James South MA has a fabulous article on L-Tryptophan
VINPOCETINE--Vinpocetine might be especially useful during a kundalini awakening! Vinpocetine is a supplement made from the periwinkle plant which improves blood circulation, oxygen uptake and glucose utilization by the brain. It increases ATP levels in the brain and stops the blood from becoming thick. Headaches, heart tension, panic, depression, ringing in the ears and impairment of thinking should be improved by the use of Vinpocetine during awakening; especially in conjunction with fat-soluble antioxidants and anti-inflammatory agents.
Researchers found that vinpocetine significantly reduced oxidative stress and inhibited free radical (ROS) formation up to 83%. It was found that the antioxidant effects of vinpocetine contributed to reducing neuronal damage in pathological situations. In addition it protects the body's energy supply for it inhibits the enzyme phosphodiesterase (PDE)-1, which breaks down adenosine monophosphate. Adenosine monophosphate (AMP) is an intermediary substance formed while creating the energy molecule ATP. Research investigated vinpocetine as a potential anticonvulsant treatment for epilepsy and found it to inhibit undesirable electroencephalogram (EEG) changes. Vinpocetine is capable of blocking sodium channel activity, leading to a decrease in the amplitude of the action potential and suggests a potential use in various sensory abnormalities arising from abnormal peripheral nerve activity and for heart arrhythmia. Vinpocetine also is an effective analgesic in neuropathic pain and possibly chronic inflammatory pain.
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